Syn Ake

Take Charge of Wrinkles

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Scientific Name: {Di-peptide Diaminobutyroyl Benzyl-amide Di-acetate}
Common Name: {Syn-Ake or Syn Ake}

While some anti-aging ingredients only relax wrinkles or tighten skin, Syn-Ake does both. Many people have products with peptides that only relax wrinkles because they don't have relatively smooth areas.

Smoothing is not a problem with Syn-Ake wrinkle-smoother peptides.

It not only works on lines caused by facial muscle cell contractions (you know, the 11s, the frown lines in between the brows) but also provides a smoother, firming lift on creases.

This peptide is inspired by nature and is based on the Temple Viper's venom. It's a synthetic tripeptide that mimics the effects of the venom. While it sounds poisonous and dangerous to use, it's not. It's an amino acid sequence or peptide (protein) with fantastic benefits.

SYN®-AKE is based on the principle of the Waglerin-1 component.

This tripeptide works magic on your skin. It has a powerful freezing effect that can help delay the onset of early aging and decrease the depth of wrinkles in mature complexions.

It is an all-around must-have if you experience expression lines around the mouth, forehead, crow's feet, and lip lines.

Most of us don't commonly think of venom regarding skincare. But it does have some significant advantages. The cosmetic ingredient paralyzes muscles and, in turn, smooths them out so that they don't contract.

Mimic Wrinkles

Over time, our facial muscles begin to "remember" their place — the muscles contract time after time. When this happens, the muscle is tight. It starts to create a crease, which eventually leads to mimic wrinkles.

They can be reversed by nerve impulses that send messages to the ACh receptors. As a result, the muscular nicotinic acetylcholine receptor (mnAChR) is blocked, keeping ion channels closed, and the sodium ion (Na+) is not absorbed.

Syn-Ake relaxes the muscles. It also helps the facial muscles forget their placement and firm up the facial area, creating a smoother, unwrinkled space. It's highly effective when used in a 5% concentration and, with consistency, has the best cumulative effects.

You will love the change you see as your face returns to its rightful place. You'll love that you can still enjoy life and laugh without worrying about your face wrinkling like a prune.

Some anti-aging ingredients provide instantaneous results. However, you must use the cream to maintain those results. Syn-Ake delivers instant gratification, and those results are stacked with continued use.

As the skin ages, most women begin to see wrinkles due to muscle contractions under the skin and sagging skin. In addition, repeated use of muscles creates wrinkles on the skin's surface.

Over time, those muscles become contracted perpetually, and the fine lines become permanent.

Simultaneously, the face loses its inherent elasticity, and women begin seeing drooping skin around the eyes, especially around the chin and neck. Previously, you could solve only one of these problems with a single ingredient.

Now, DSM provides an anti-aging solution with a Syn-Ake product, a patented ingredient from the Swedish company Pentapharm LTD.

Syn-Ake Wrinkle Smoothing Peptide

It tightens the skin's look and reduces the muscle contractions that cause crow's feet, parentheses around the mouth, and forehead lines. It works to inhibit the transmission of impulses that cause those muscles to tense up. Finally, it begins to smooth and relax the look of fine lines and wrinkles.

Typically, this would cause more skin to sag away from the face. However, this unique peptide also encourages elastin and collagen to return to normal levels. As a result, more elastin and collagen produce younger-looking faces.

You will see your complexion tighten with continued use, your jowls lifted, and more supple, hydrated, and plump skin.

Studies have shown that using Syn-Ake for four weeks and twice a day can smooth the look of wrinkles by more than 50%. This active peptide is exceptionally effective and has been tested thoroughly.

Compared to measures like Botox, it can provide similar results without even getting an injection.

Many women have begun using a wrinkle-relaxing serum-infused product with Syn-Ake instead of resorting to Botox, as it is safer, effective, and eliminates the need for needles.

Benefits of Smoothing Peptides in Skincare

1. Reduction of Fine Lines and Wrinkles: Peptides signal the skin to produce more collagen, which can lead to a smoother and more youthful complexion.

2. Skin Relaxation: Certain peptides, like Argireline (acetyl hexapeptide-3), are known to help relax facial muscles, thereby reducing the appearance of expression lines.

3. Improved Skin Elasticity: By promoting collagen production, peptides can help the skin remain supple and bounce back more easily from facial expressions that can lead to lines.

4. Enhanced Skin Barrier: Some peptides can strengthen the skin barrier, resulting in better hydration retention and protection against external stressors.

Why is Syn-Ake Considered the Best Smoothing Peptide?

Syn-Ake is a synthetic peptide that mimics the activity of a component found in the venom of the Temple Viper snake. Here's why it's often heralded as a standout smoothing peptide:

1. Muscle Relaxation: Just as snake venom can lead to muscle paralysis, Syn-Ake acts to reduce muscle cell contractions, leading to a smoother skin surface, especially in areas with expression lines.

2. Rapid Results: Many users report noticeable reductions in the appearance of fine lines and wrinkles in a relatively short amount of time when using products containing Syn-Ake. Remember, it takes 30 days to see the full effects.

3. Complementary to Other Ingredients: Syn-Ake can be effectively combined with other skincare ingredients for a comprehensive anti-aging regimen.

4. Safe Alternative: For those looking for non-invasive alternatives to treatments like Botox, Syn-Ake offers a topical solution that can achieve similar, albeit temporary, smoothing effects.

5. Consistent Efficacy: Various clinical studies have showcased Syn-Ake's ability to provide significant anti-wrinkle benefits, reinforcing its reputation in the skincare community.

It's important to note, however, that while Syn-Ake is a powerful smoothing peptide, the best peptide for an individual can vary based on their specific needs, skin type, and concerns.

Wrinkle Injections VS. Topicals

The most common anti-wrinkle injection is Botox. Many other brand-name injectables are Dysport or Bolotero.

While these are mild alternatives to Botox, they are not as strong.

Treatment areas include the 11's - the lines between the brows, sometimes called furrows — forehead lines, crow's feet, and the fine lines in the under-eye hollows.

Anti-wrinkle injections instantly remove wrinkles. The downside is that they are expensive, require maintenance every two to three months, and inject toxins into your facial muscles.

Facial fillers instantly treat volume loss and minimize wrinkles. Hyaluronic Acid is the most commonly used ingredient. It is a natural material in the skin and is injected into the dermis.

The result is a wrinkle-free face. Many injections take 5 to 10 years off of your appearance immediately. They can also change the shape of your face. Many treatments "fill" creases and lines, but they can even restore volume and enhance the shape of the face.

Dermal Facial Fillers Target

• Lips lines
• Nasolabial folds, the marionette lines around the mouth
• Cheeks
• Under-eye hollows
• Eyebrows
• Bunny lines, the horizontal crease on your nose below your forehead

While dermal facial fillers are more natural since they contain hyaluronic acid, some wrinkle fillers are not.

The most popular brand, Juvederm, is made from Hyaluronic Acid. Radiesse is an example of a wrinkle-filler that uses calcium microspheres to enhance your body's collagen production and treat volume loss. However, they have side effects such as bruising and require downtime. Fillers tend to last longer than anti-wrinkle injections but are even more costly.

5 Benefits of Syn-Ake

Topicals are the safest and least expensive option to treat the appearance of wrinkles, fine lines, and creases. There is no downtime and no costly trips to the dermatologist. In addition, using a topical treatment twice daily can help minimize wrinkles.

1. Wrinkle Reduction: Syn-Ake is a peptide that mimics the effects of snake venom, helping to relax facial muscles. This action can lead to a reduction in the appearance of fine lines and wrinkles.

2. Smoothing Effect: The muscle-relaxing properties of Syn-Ake can result in a smoother skin texture, making it an effective ingredient for achieving a more youthful complexion.

3. Non-Invasive: Unlike surgical procedures or injections, products containing Syn-Ake offer a non-invasive alternative to combatting the signs of aging, making it a popular choice for those seeking to avoid needles and recovery time.

4. Natural-Looking Results: Syn-Ake provides a natural and subtle improvement in the skin's appearance, avoiding the frozen or unnatural look that can sometimes be associated with other anti-aging treatments.

5. Collagen Support: While Syn-Ake primarily focuses on muscle relaxation, its use can indirectly support collagen production over time by preventing repetitive muscle movements that can lead to wrinkles. This helps maintain skin elasticity and firmness.

Synergistic Beauty: The Cumulative Impact of Syn-Ake

Syn-Ake does have a cumulative effect. You can achieve maximum benefits in 30 days. You won't be disappointed, as studies have shown this tripeptide to minimize wrinkle depth by 30%.

Obtain a youthful appearance with the use of topicals. Peptides are the driving force behind the anti-aging benefits. Therefore, using a combination of peptides for the best results is best.

Clinical studies have shown that anti-aging peptides such as Matrixyl 3000 can help you look 5 to 10 years younger in as little as two months when used twice daily.

Combining Matrixyl 3000, Syn-Ake, Pepha Tight, and Syn-Coll is one of the best topical serums for a younger-looking natural appearance.

Sources:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266942/
https://pubchem.ncbi.nlm.nih.gov/compound/Syn-ake
https://www.dsm.com/personal-care/en_US/products/skin-bioactives/syn-ake.html

About the Author
Kari Thomas wrote this article.